GeneSet Cholesterol biosynthesis (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
+oo -5.2 0.00183 15.0 4.0 0.28
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000116133 DHCR24 NonAssociatedWithProgression
ENSG00000172893 DHCR7 o--b
ENSG00000147155 EBP o--b
ENSG00000079459 FDFT1 o+-
ENSG00000152904 GGPS1 NonAssociatedWithProgression
ENSG00000113161 HMGCR +oo
ENSG00000112972 HMGCS1 oo-
ENSG00000132196 HSD17B7 o+o
ENSG00000067064 IDI1 +-o
ENSG00000143815 LBR +oo
ENSG00000160285 LSS +oo
ENSG00000167508 MVD NonAssociatedWithProgression
ENSG00000110921 MVK ---
ENSG00000147383 NSDHL +-o
ENSG00000163344 PMVK o--a
ENSG00000109929 SC5DL o++b
ENSG00000104549 SQLE +oo
ENSG00000149809 TM7SF2 o-o