GeneSet mTORC1-mediated signalling (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--a -3.0 0.01417 7.0 4.0 0.99
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000103319 EEF2K o++a
ENSG00000063046 EIF4B o--a
ENSG00000187840 EIF4EBP1 o--b
ENSG00000114867 EIF4G1 ---
ENSG00000167965 MLST8 o--a
ENSG00000198793 MTOR NonAssociatedWithProgression
ENSG00000106615 RHEB NonAssociatedWithProgression
ENSG00000137154 RPS6 o--a
ENSG00000108443 RPS6KB1 NonAssociatedWithProgression
ENSG00000141564 RPTOR o--a