GeneSet TRAF6 mediated NF-kB activation (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
--o -3.5 0.00951 12.0 3.0 0.37
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000142192 APP o++b
ENSG00000213341 CHUK NonAssociatedWithProgression
ENSG00000189403 HMGB1 o--b
ENSG00000104365 IKBKB o++a
ENSG00000073009 IKBKG --o
ENSG00000095015 MAP3K1 o--a
ENSG00000088888 MAVS --o
ENSG00000109320 NFKB1 o++a
ENSG00000077150 NFKB2 NonAssociatedWithProgression
ENSG00000100906 NFKBIA o-o
ENSG00000104825 NFKBIB ---
ENSG00000173039 RELA o--a
ENSG00000181481 RNF135 --o
ENSG00000127191 TRAF2 o--b
ENSG00000175104 TRAF6 NonAssociatedWithProgression
ENSG00000121060 TRIM25 NonAssociatedWithProgression