GeneSet Regulation of pyruvate dehydrogenase (PDH) complex (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
UpRegulated -2.8 0.02363 5.0 4.0 1.35
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000150768 DLAT NonAssociatedWithProgression
ENSG00000091140 DLD NonAssociatedWithProgression
ENSG00000131828 PDHA1 o+-
ENSG00000168291 PDHB o+o
ENSG00000110435 PDHX o+o
ENSG00000152256 PDK1 NonAssociatedWithProgression
ENSG00000067992 PDK3 o++b
ENSG00000164951 PDP1 o++b