GeneSet Purine metabolism (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
-+o -3.2 0.01179 16.0 4.0 0.75
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000196839 ADA -o-
ENSG00000156110 ADK -+o
ENSG00000239900 ADSL -+o
ENSG00000035687 ADSS NonAssociatedWithProgression
ENSG00000185100 ADSSL1 NonAssociatedWithProgression
ENSG00000116337 AMPD2 NonAssociatedWithProgression
ENSG00000198931 APRT o--b
ENSG00000138363 ATIC o--b
ENSG00000121691 CAT -+o
ENSG00000156136 DCK ---
ENSG00000114956 DGUOK NonAssociatedWithProgression
ENSG00000159131 GART NonAssociatedWithProgression
ENSG00000100938 GMPR2 -+o
ENSG00000163655 GMPS o--a
ENSG00000233276 GPX1 ---
ENSG00000165704 HPRT1 NonAssociatedWithProgression
ENSG00000106348 IMPDH1 o--a
ENSG00000178035 IMPDH2 o-o
ENSG00000125458 NT5C o-o
ENSG00000076685 NT5C2 o--b
ENSG00000128050 PAICS NonAssociatedWithProgression
ENSG00000178921 PFAS ---
ENSG00000198805 PNP o--a
ENSG00000128059 PPAT NonAssociatedWithProgression