GeneSet NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
--o -4.6 0.00318 7.0 3.0 0.21
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000064012 CASP8 +-o
ENSG00000213341 CHUK NonAssociatedWithProgression
ENSG00000168040 FADD o--b
ENSG00000104365 IKBKB o++a
ENSG00000073009 IKBKG --o
ENSG00000088888 MAVS --o
ENSG00000137275 RIPK1 o--b
ENSG00000181481 RNF135 --o
ENSG00000121060 TRIM25 NonAssociatedWithProgression