GeneSet Meiosis (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--b -2.3 0.03619 34.0 10.0 4.7
oo- -3.4 0.01001 34.0 4.0 0.65
DownRegulated -3.0 0.01562 34.0 28.0 20.08
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000102977 ACD o+-
ENSG00000149311 ATM NonAssociatedWithProgression
ENSG00000175054 ATR NonAssociatedWithProgression
ENSG00000197299 BLM ---
ENSG00000012048 BRCA1 NonAssociatedWithProgression
ENSG00000123374 CDK2 oo-
ENSG00000135446 CDK4 o--a
ENSG00000101191 DIDO1 o-o
ENSG00000188486 H2AFX ---
ENSG00000164032 H2AFZ o-o
ENSG00000163041 H3F3A NonAssociatedWithProgression
ENSG00000137259 HIST1H2AB oo-
ENSG00000180573 HIST1H2AC NonAssociatedWithProgression
ENSG00000196226 HIST1H2BB o--b
ENSG00000158373 HIST1H2BD NonAssociatedWithProgression
ENSG00000197459 HIST1H2BH oo-
ENSG00000196176 HIST1H4A ---
ENSG00000183558 HIST2H2AA3 o--b
ENSG00000184678 HIST2H2BE NonAssociatedWithProgression
ENSG00000113368 LMNB1 o--b
ENSG00000076242 MLH1 o--b
ENSG00000121211 MND1 o++a
ENSG00000204410 MSH5 NonAssociatedWithProgression
ENSG00000104320 NBN NonAssociatedWithProgression
ENSG00000128513 POT1 o++b
ENSG00000131470 PSMC3IP o-o
ENSG00000164754 RAD21 o--b
ENSG00000113522 RAD50 NonAssociatedWithProgression
ENSG00000051180 RAD51 NonAssociatedWithProgression
ENSG00000108384 RAD51C o+-
ENSG00000101773 RBBP8 NonAssociatedWithProgression
ENSG00000117748 RPA2 oo-
ENSG00000106399 RPA3 o++b
ENSG00000072501 SMC1A o--a
ENSG00000108055 SMC3 NonAssociatedWithProgression
ENSG00000118007 STAG1 NonAssociatedWithProgression
ENSG00000101972 STAG2 o--b
ENSG00000066923 STAG3 o--b
ENSG00000164828 SUN1 o--a
ENSG00000100242 SUN2 o-o
ENSG00000161860 SYCE2 o--a
ENSG00000131018 SYNE1 o++b
ENSG00000054654 SYNE2 o--b
ENSG00000147601 TERF1 NonAssociatedWithProgression
ENSG00000132604 TERF2 o--a
ENSG00000166848 TERF2IP o--b
ENSG00000092330 TINF2 o--b
ENSG00000177302 TOP3A o--a
ENSG00000103275 UBE2I o--a