GeneSet HIV Abortive elongation of HIV-1 transcript in the absence of Tat (HIV_Collection.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--b -2.3 0.04625 17.0 6.0 2.35
DownRegulated -2.8 0.02047 17.0 15.0 10.04
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000188986 COBRA1 o--b
ENSG00000060069 CTDP1 ---
ENSG00000125651 GTF2F1 o--a
ENSG00000188342 GTF2F2 NonAssociatedWithProgression
ENSG00000136937 NCBP1 o+-
ENSG00000114503 NCBP2 o--b
ENSG00000181222 POLR2A ---
ENSG00000047315 POLR2B +oo
ENSG00000102978 POLR2C NonAssociatedWithProgression
ENSG00000144231 POLR2D o--b
ENSG00000100142 POLR2F NonAssociatedWithProgression
ENSG00000168002 POLR2G NonAssociatedWithProgression
ENSG00000163882 POLR2H o-o
ENSG00000105258 POLR2I --o
ENSG00000005075 POLR2J ---
ENSG00000177700 POLR2L o-o
ENSG00000204356 RDBP o-o
ENSG00000213246 SUPT4H1 o--a
ENSG00000196235 SUPT5H o--b
ENSG00000101158 TH1L o--b
ENSG00000185049 WHSC2 o--b