PEACHi
GeneSet DAMAGED_DNA_BINDING (GO_-_Molecular_Function.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--a -2.7 0.04505 11.0 5.0 1.56
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000137074 APTX NonAssociatedWithProgression
ENSG00000167986 DDB1 o--a
ENSG00000134574 DDB2 o--a
ENSG00000175595 ERCC4 o-o
ENSG00000168496 FEN1 NonAssociatedWithProgression
ENSG00000103152 MPG o--a
ENSG00000095002 MSH2 +oo
ENSG00000116062 MSH6 o--a
ENSG00000114026 OGG1 o--a
ENSG00000051341 POLQ +o+
ENSG00000135945 REV1 ---
ENSG00000139372 TDG NonAssociatedWithProgression
ENSG00000136936 XPA o++b
ENSG00000154767 XPC o--b