GeneSet REGULATION_OF_PROTEIN_STABILITY (GO_-_Biological_Process.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--b -3.1 0.0415 7.0 4.0 0.97
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000137074 APTX NonAssociatedWithProgression
ENSG00000087586 AURKA +-o
ENSG00000015133 CCDC88C o--b
ENSG00000168564 CDKN2AIP NonAssociatedWithProgression
ENSG00000136152 COG3 NonAssociatedWithProgression
ENSG00000100225 FBXO7 o-o
ENSG00000107937 GTPBP4 o--b
ENSG00000100099 HPS4 NonAssociatedWithProgression
ENSG00000063241 ISOC2 o--b
ENSG00000198625 MDM4 o-o
ENSG00000171862 PTEN NonAssociatedWithProgression
ENSG00000117758 STX12 NonAssociatedWithProgression
ENSG00000154144 TBRG1 o--b