GeneSet Destabilization of mRNA by KSRP (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
DownRegulated -2.7 0.02836 12.0 11.0 7.09
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000142208 AKT1 ---
ENSG00000172795 DCP2 o-o
ENSG00000083520 DIS3 o--a
ENSG00000171311 EXOSC1 NonAssociatedWithProgression
ENSG00000130713 EXOSC2 o--b
ENSG00000107371 EXOSC3 NonAssociatedWithProgression
ENSG00000178896 EXOSC4 --o
ENSG00000077348 EXOSC5 o--a
ENSG00000223496 EXOSC6 o--a
ENSG00000075914 EXOSC7 NonAssociatedWithProgression
ENSG00000123737 EXOSC9 o--b
ENSG00000088247 KHSRP o--b
ENSG00000112062 MAPK14 o++b
ENSG00000140694 PARN o-o
ENSG00000164924 YWHAZ o--b