GeneSet CHROMATIN_MODIFICATION (GO_-_Biological_Process.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
DownRegulated -3.3 0.01326 28.0 24.0 16.54
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000136518 ACTL6A o--a
ENSG00000117713 ARID1A o--b
ENSG00000171634 BPTF NonAssociatedWithProgression
ENSG00000005339 CREBBP NonAssociatedWithProgression
ENSG00000181090 EHMT1 NonAssociatedWithProgression
ENSG00000116478 HDAC1 ---
ENSG00000100429 HDAC10 o--b
ENSG00000163517 HDAC11 -oo
ENSG00000196591 HDAC2 NonAssociatedWithProgression
ENSG00000171720 HDAC3 ---
ENSG00000068024 HDAC4 o--b
ENSG00000094631 HDAC6 o--a
ENSG00000147099 HDAC8 oo-
ENSG00000119969 HELLS +o+
ENSG00000137309 HMGA1 o--b
ENSG00000086758 HUWE1 o-o
ENSG00000103510 MYST1 o--b
ENSG00000083168 MYST3 +-o
ENSG00000156650 MYST4 NonAssociatedWithProgression
ENSG00000132780 NASP o--a
ENSG00000165671 NSD1 NonAssociatedWithProgression
ENSG00000163939 PBRM1 NonAssociatedWithProgression
ENSG00000167085 PHB NonAssociatedWithProgression
ENSG00000132600 PRMT7 o--a
ENSG00000162521 RBBP4 NonAssociatedWithProgression
ENSG00000239306 RBM14 o--a
ENSG00000100784 RPS6KA5 NonAssociatedWithProgression
ENSG00000048649 RSF1 +-o
ENSG00000119335 SET o--b
ENSG00000096717 SIRT1 +-o
ENSG00000068903 SIRT2 --o
ENSG00000124523 SIRT5 --o
ENSG00000173473 SMARCC1 o--a
ENSG00000139613 SMARCC2 --o
ENSG00000066117 SMARCD1 NonAssociatedWithProgression
ENSG00000213246 SUPT4H1 o--a
ENSG00000162227 TAF6L ---
ENSG00000177889 UBE2N o--a
ENSG00000147548 WHSC1L1 o--b